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Peptide-protein interactions play fundamental roles in cellular processes and are crucial for designing peptide therapeutics. Here, the authors present a deep learning …
Natural bioactive peptides are suitable candidates for preventing the development of Type 2 diabetes (T2D), by reducing the various risk factors. The aim of this …
Discover collagen peptides: their health benefits, biological functions, and applications in skincare, joint health, and overall wellness.
In order to investigate the structural basis of peptide-protein interactions, we have created a non-redundant database of high-resolution structures of peptide-protein …
Höga eller låga nivåer av lipider och blodfetter kan öka risk för hjärt-kärlsjukdom. Här får du veta mer om lipider och blodfetter och varför de är viktiga.
Exosomes are secreted extracellular vesicles that mediate intercellular transfer of cellular contents and are attractive vehicles for therapeutic delivery of bimolecular cargo …
OverviewFunction (translocation)StructureCo-translational versus post-translational translocationSecretion efficiency determinationNucleotide level featuresAlternate secretion mechanismsNonclassical sequences
A signal peptide (sometimes referred to as signal sequence, targeting signal, localization signal, localization sequence, transit peptide, leader sequence or leader peptide) is a short peptide (usually 16-30 amino acids long) present at the N-terminus (or occasionally nonclassically at the C-terminus or internally) of most newly synthesized proteins that are destined toward the secretory pathway. These proteins include those that reside either inside certain organelles (the endoplasmic reticulum
a, Region structures of the five SP types.Twin arginine (RR)-translocated SPs feature a twin-arginine motif, while SPs cleaved by SPase II feature a C-terminal lipobox. …